1up! is a passive item.
- Grants an extra life.
- On resurrection, the mushroom that follows Isaac will disappear and Isaac will respawn in the previous room with all his previous Red Heart containers at full health.
- If Isaac has no Red Heart containers, he'll respawn with 1/2 Soul Heart instead.
- The 1up! mushroom begins following Isaac like a familiar upon pickup, but doesn't do anything.
- This item belongs to the Fun Guy set. Collecting three items from this set will transform Isaac into a walking mushroom.
- Resurrection items activate in a set order. 1up! is 2nd in this order after Soul of Lazarus.
- ???/ Tainted ???/ Tainted Bethany/ Tainted Forgotten will respawn with 3 soul hearts.
- The Forgotten will respawn with 3 filled bone hearts (notably more than his starting HP) and The Soul with whatever soul and black hearts he had on death.
- Dying as The Soul respawns him with a 1/2 soul heart and The Forgotten with whatever bone hearts he had on death.
- Dark Judas/ Tainted Judas will respawn with 2 black hearts.
- It is possible to collect more than one 1up! items, resulting in multiple extra lives.
PS4 PC CWSQ TNM8 (first Secret Room right from spawn)
- This is a reference to the Mario franchise, where collecting a green mushroom would give you an extra life.
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