Guppy's Paw

Guppy's Paw is an activated item.

Effects

 * Upon use, converts one Red Heart Container into three Soul Hearts.

Synergies

 * Allows Isaac to attain up to 10 Heart Containers and 1 Soul Heart.
 * : Allows Isaac to attain up to 12 Heart Containers or any combination of Heart Containers and Soul Hearts.

Interactions

 * Broken Remote: The teleport will activate whenever Guppy's Paw is used, even if Isaac has no Red Heart containers to trade. This can give, , or  (or other characters with no Red Hearts) the ability to teleport an infinite number of times without any cost.
 * : No effect.
 * : Guppy's Paw will take away one Coin Heart, but will only grant Blue Flies in return.
 * : Converts the temporary Red Heart container into three Soul Hearts (however, Isaac will still lose one Red Heart container upon leaving the room if he has any left).
 * : Guppy's Paw will remove one Heart Container in exchange for Soul Heart charges. This will kill Bethany if she has no health left afterward.

Trivia

 * This item appeared in The Binding of Isaac: Wrath of the Lamb.
 * It is also a reference to Edmund McMillen's cat Guppy.
 * This item is used in Baptism by Fire (challenge #38).

Seeds
6QN8 VV6L (Curse Room adjacent to spawn)