Pestilence

Pestilence is a Harbinger that can appear in all environments of Chapter 2.

Phase 1

 * Floats around the room, leaving a large trail of damaging Green Creep.
 * Fires an projectile at Isaac, which leaves Green Creep on impact.
 * Summons two Chargers or Spitties and can have a maximum of four summons.
 * Any Chargers or Spitties caught in Pestilence's Ipecac explosion will be killed.

Phase 2
After taking enough damage, Pestilence's head will explode, beginning the second phase.
 * No longer moves around the room but slowly drifts around, leaving Green Creep.
 * Continues to fire Ipecac projectiles at Isaac, but at a faster rate.
 * Summons two Attack Flies.

Pestilence deals a whole heart of contact damage in both phases, though without flight Isaac is more likely to be damaged by the Green Creep instead.

Champion Versions

 * Pale Grey: Leaves a trail of slowing White Creep instead of Green Creep, shoots 6 projectiles in all directions instead of an Ipecac shot and spawns Trites instead of Chargers or Spitties. It spawns Spiders instead of Attack Flies in Phase 2.

Trivia

 * Pestilence appeared in the original The Binding of Isaac.
 * Pestilence is not directly one of the Four Horsemen of the Apocalypse and is not present with the other Horsemen in Revelations (Revelation 6:2). The canonical Four Horsemen are Conquest (white), War (red), Famine (black), and Death (pale).
 * However, pestilence is featured as one of God's "four disastrous acts of judgment" alongside sword, famine, and wild beasts (Ezekiel 14:21), which, in some cases, can be interpreted as symbolic of the Horsemen- as the acts of judgement are often used by God for destructive purposes throughout the Bible.
 * These four acts are given to the Horseman of Death to perform (Revelation 6:8) despite the contradictory fact that famine, the attribute of a completely separate Horsemen is among the acts.
 * Despite not being a true Horseman, Ultra Pestilence still appears instead of an ultra version of Conquest during The Beast fight.
 * Pestilence means a fatal disease epidemic.
 * Pestilence is the only Harbinger that does not have a charge attack.
 * Pestilence’s head resembles The Husk.
 * Pestilence makes a "Hey!" sound when launching explosive projectiles at Isaac. Famine makes the same noises when spitting shots at Isaac at its second phase.

Pestilence