Plan C

Plan C is an unlockable activated item added in Afterbirth †.

Effect

 * Upon use, deals 9,999,999 damage to every enemy in the room, then kills Isaac 3 seconds later.

Trivia

 * This is a reference to the "Morning After" pill that prevents pregnancy, commonly referred to as "Plan B". It's also a reference to a "cyanide pill" that is fatally poisonous and can be deliberately taken to commit suicide. It's likely that the item is called "Plan C" because it is too late for a "Plan B" to prevent Isaac from being born; so the "next best thing", Plan C, is for Isaac to kill himself. The letter is also coincidentally the initial for cyanide.
 * This item is found in 5 item pools, the highest count amongst all items, but its lowered weight of 20% offsets its presence.
 * Plan C's sprite is a red-tinted.
 * In Afterbirth+, the pickup quote for the item was "Use with caution".

Plan C