Clicker

Clicker is an active item added in The Binding of Isaac: Afterbirth †.

Effect

 * Transforms Isaac into a random character and removes the last item collected (not including Clicker).
 * All stat changes of the new character are applied.

Interactions

 * Isaac will transform twice and have the last two picked up items removed.
 * Stat upgrades given by removed items are retained, and the best stats of each character you turn into are retained, possibly creating some powerful characters, like Tainted Keeper with all the Berserk stats of Tainted Samson.

Seeds
PW44 Y9WH (Treasure Room at spawn in Normal mode, go south in Hard mode)