Epic Fetus

Epic Fetus is an unlockable passive item.

Effects

 * Isaac's tears are replaced with guided missiles. Pressing the fire buttons spawns a crosshair that can be moved freely, summoning a missile to its position from above 1.5 seconds later.
 * Missiles deal 20 times Isaac's damage.

Synergies

 * / Bookworm/Conjoined//: Fires a barrage of missiles.
 * Missiles explode in a large cross-shaped blast, with each explosion dealing 0.75x times damage. Unlike with regular bombs, getting hit by every separate explosion from Epic Fetus won't decrease the damage for each successive explosion, drastically increasing damage.
 * Every missile explosion leaves a large, lasting pool of red creep.
 * /: Each missile has a 50% chance to deal 20 or 40 points more damage, respectively.
 * /: Missiles gain a poison effect.
 * Explosions leave behind a cloud of poison gas that will poison enemies in contact with it aside from the main target.
 * Missile explosions shoot ten blood lasers in all directions.
 * Missile explosions have a chance to shoot four Brimstone lasers in the cardinal directions. The chance scales with Isaac's luck.
 * Missile explosions will cloud up the screen, briefly confusing and dealing 10 damage to all enemies in the room.
 * /: Missile explosions leave behind a fire that damage enemies on contact. Fire Mind's burn effect is overridden.
 * : The charge attack is replaced by a missile in the Forgotten's hand and a crosshair that may be moved for an indefinite amount of time. The missile is thrown at the crosshair when all attack buttons are released, with an additional melee swing in the same direction. The melee attack is unaffected.
 * Missile explosions have a small chance of spawning pickups.
 * Homing tears: The crosshair slowly slides towards enemies.
 * /Pyromaniac: Isaac becomes immune to his own airstrikes.
 * Missiles have a poison effect, have a larger blast radius and deal drastically increased damage, as the +40 damage from Ipecac is run through the damage multiplier of Epic Fetus.
 * Adds flat +2 damage instead of +40. Explosions leave behind a cloud of poison gas that will poison enemies in contact with it aside from the main target.
 * Missile explosions shoot a ring of ten knives.
 * 2 to 4 additional crosshairs orbit the main crosshair, and missiles are fired onto each crosshair.
 * Every missile explosion leaves a small, lasting pool of creep.
 * Explosions have a chance to be affected by any of the bomb-modifier effects that synergize with Epic Fetus.
 * Increased tear delay, but massively increases the missiles' blast radius and damage, as Polyphemus' damage multiplier is run through the damage multiplier of Epic Fetus.
 * Missile explosions fire ten tears in all directions. The shrapnel's damage is not run through the damage multiplier of Epic Fetus.
 * The chance for the effect to proc is dependent of Isaac's luck. Chance goes up to 100% at 30 luck.
 * Enemies get drawn towards the crosshair.
 * Both fire normally. Missile explosions shoot ten Technology beams in all directions.
 * Missile explosions shoot ten Technology beams in all directions.
 * Missile explosions shoot ten Technology beams in all directions.

Interactions

 * : Missile explosions retain the knockback boost, so enemies that survive the blast will be knocked back far.
 * : Overridden by Epic Fetus. Stat effects are still applied.
 * Azazel's mini-Brimstone is overridden by Epic Fetus.
 * /////: No effect.
 * Overridden by Epic Fetus.
 * Reduces Isaac's tear delay by 20%. Missiles can't be charged.
 * Overridden by Epic Fetus.
 * Overridden by Epic Fetus.
 * Overridden by Epic Fetus.
 * Overridden by Epic Fetus.
 * Stat effects apply and the crosshair gains a homing effect, but missiles do not have a damaging aura.
 * Homing tears: Overridden by Epic Fetus.
 * : Incubus fires normal tears while the crosshair is being aimed.
 * Incubus fires a missile alongside Isaac's.
 * Overridden by Epic Fetus.
 * Overridden by Epic Fetus.
 * Overridden by Epic Fetus.
 * : No effect.
 * No effect.
 * //: Fires only normal tears, not missiles.
 * Not recommended. Damage of missiles is drastically reduced, and unlike normal tears, the fire rate will not significantly increase.
 * Overrides Epic Fetus.
 * Overridden by Epic Fetus.
 * : Not recommended. Technology 2 is overridden by Epic Fetus, but the damage multiplier is still applied, massively reducing the missiles' damage.
 * Both fire normally.
 * Does not reduce missiles' damage, and both fire normally at the cost of a slightly higher delay between each crosshair appearing.
 * Overridden by Epic Fetus.
 * Makes two missiles drop in quick succession, and control of the crosshair is rotated 45 degrees clockwise. Not recommended, as it makes controlling the crosshair harder.

Trivia

 * In the original game it was possible to control the crosshair with the mouse. This was removed in Rebirth.
 * Mouse control can however be re-enabled by editing the  file in   and changing the line   into  . Also useful for The Ludovico Technique.
 * The Dr. Fetus and Epic Fetus items are based off of Dr. Fetus, the main villain in Super Meat Boy which is a game by Edmund McMillen (the creator of The Binding of Isaac: Rebirth).
 * In Wrath of the Lamb, Epic Fetus could be found in both the Secret Room and Treasure Room item pools.
 * Epic Fetus was added to the Secret Room item pool.
 * This item is used in Glass Cannon (challenge #11).

Seeds
GOBD W8TB (Treasure Room adjacent to spawn) C6AK HY1N (First floor Secret Room, ←↓ from spawn) 8ETR M2M9 (First floor Treasure Room) B2B2 3J9G (First floor Treasure Room) 8G4J JFH8 (Treasure Room adjacent to spawn)