Book of Virtues

Book of Virtues is an active/passive item added in The Binding of Isaac: Repentance.

Effects

 * On use, spawns a wisp that orbits Isaac and fires small spectral tears alongside him. The wisps are damaged and eventually destroyed if they make contact with an enemy, an enemy shot or an explosion.
 * When a wisp is destroyed, the sound of fire being extinguished plays.
 * A normal wisp is white and blue, has 2 health and spectral tears which deal 1.6-2.4 damage, and is summoned in the middle ring.
 * A wisp's health can be determined by its size, shrinking as its health decreases.
 * Multiple wisps can exist at once. Some combinations have an upper limit of 26 wisps: an inner counterclockwise ring of 6, a middle clockwise ring with 8, and an outer counterclockwise ring of 12.
 * Passively, the Book will combine with other activated items, possibly granting special effects on the created wisps. The recharge time will be based on the other item.
 * While held, guarantees the first Devil/Angel Room encountered to be an Angel Room, and increases the overall chance of getting one by 12.5%
 * Allows for Angel Rooms to appear even if a Devil Deal was taken before.

Combinations

 * The wisps are black-glowing flies with extra HP do not fire tears.
 * Spawns up to 8 normal wisps, filling up the middle ring.
 * Middle ring. The wisps look like "A Pony", and charges ahead into enemies when attacked.
 * The wisps look like small bombs, and become troll bombs when destroyed.
 * Spawns a dark wisp that orbits the locked enemy and shoots at them. When the enemy dies, the wisp despawns.
 * Outer ring. The wisps are surrounded with green stink clouds, sometimes trigger The Bean's effect when destroyed.
 * Spawns a pale wisp with extra HP that does not fire tears.
 * The wisps are small Isaac heads with white flame, shooting tears which have a rare chance to apply the effect, causing other enemies to attack them.
 * Inner ring. The wisps are white, have extra health, and fire -effect tears.
 * Middle Ring. The wisps are black and fire tears with a magnetic effect.
 * The Wisps are a floating card, and take up the space of a normal wisp. Enemies killed by the wisps have a 15% chance to drop a card.
 * Middle ring. The wisps are red, and shoot blood tears.
 * Middle ring. The wisps shoot arcing green tears, with a 1/10 chance to shoot an explosive tear.
 * Middle ring. The wisps are black and red and shoot high-damage blood tears.
 * The wisps are tiny skulls and fire tears which look like bones. When destroyed, they spawn a friendly Bony or a Black Bony. The wisps orbit in reverse.
 * Inner ring. The wisps become tiny crosses that do not fire tears, spawn a Harbinger familiar for the current room when destroyed.
 * Middle ring. The wisps become tiny spinning question marks. When they are destroyed, they will have the same effects as getting hit with.
 * Middle ring. The wisps have 1 health, but will not be damaged by blocking projectiles. (Can only be destroyed on contact with enemies.)
 * Grants a random wisp based on one of the seven deadly sins. The wisp spawned isn't linked to the pickup dropped
 * Pride: a blue bomb wisp in the middle ring. Unlike the orange ones, their tears have no effect, they don't drop troll bombs, nor a bomb pickup on death.
 * Greed: 3 yellow coin wisps in the outer ring. Their tears may petrify enemies like Midas' Touch.
 * Wrath: an orange bomb wisp in the middle ring, which fire flaming tears. They drop troll bombs when continuously firing, and leave a bomb pickup when they die.
 * Envy: a white face-like wisp in the outer ring.
 * Lust: a randomly colored pill wisp in the inner ring. (similar to Mom's Bottle of Pills)
 * Gluttony: a heart wisp similar to Yum Heart's wisp (middle ring, takes 3 hits, may drop heart on death).
 * Sloth: a Bob's Head wisp in the middle ring. Their tears travel in an arc like Ipecac but don't explode on impact.
 * Any wisps created with The Boomerang will disappear when changing rooms. Tears fired up by those Wisps will fly back to Isaac after traveling the same range as Isaac's.
 * The wisps are Black with a dark aura, and shoot dark tears.
 * Spawns 5-6 spider-like wisps (maxed at 12) hovering on a distant orbit. They fire small spectral tears, deals contact damage, and transform into blue spiders upon destruction.
 * Creates a wisp after it's been held long enough for Isaac to take damage.
 * The wisps become tiny ghosts reminiscent of . When a tear shot by the wisp hits an enemy, there's a chance for Mom's leg to stomp on them.
 * The wisps are brownish and do not fire with Isaac, but instead auto-fire at nearby enemies like the Nugget's fly turret. The wisps are lost after leaving the room they were created in.
 * Inner ring. The wisps are white and do not shoot tears or deal contact damage, only 1 health each, release farts that knockback upon death and cannot be carried across rooms.
 * Wisp are blue and only exist within the current room. For each activation of the candle, a new wisp is added for the duration of the blue flame. If the wisp stays after the flame disappears depends on the type of charge used to activate the blue flame: For a green charge, it only stays if the generated blue flame hit an enemy. For a blue charge, the wisp always stays. Wisps are reset to one if the blue flame does not hit an enemy.
 * Spawns a purple-glowing rune wisp. Wisps fire normal tears and drop runes and soul stones when destroyed. They also have a 15% chance to drop a random rune when they kill an enemy. Even though they're colored purple, they do not have homing properties.
 * Spawns a random wisp.
 * Spawns dark green wisp glowing with dark purple light. Does not spawn a wisp if no pickups are consumed upon activation.
 * Spawns heart wisps.
 * Spawns coin wisps. Wisps have 50% chance to be doubled or destroyed upon being hit.
 * Spawns one green wisp that fires a triple shot. Some green wisps will disappear upon purchasing an item with coins.
 * When used for contact damage or destroyed, wisps create pillars of light.
 * Wisps are a crystal ball. Normal tears.
 * Spawns one normal wisp and one white-glowing wisp.
 * Two white six-sided dice wisps are spawned at the same time.
 * In addition to adding random wisps, rerolls your current wisps into ones with random effects.
 * A white wisp and a D6 wisp are spawned, and an additional D6 wisp is spawned per item rerolled.
 * Spawns one six-sided grey die wisp. When the wisp is hit it turns blue and either applies the D7 to the current room or teleports the player to the room it was used.
 * Spawns black-glowing dice wisps. Wisps fire normal tears.
 * The orange wisps reside within the inner ring and can reroll enemies occasionally with their shots.
 * Wisps are blue dice. Occasionally re-roll blocks in the room with their shots.
 * Summons a random type of wisp. Additionally summons a second random wisp if a collectible item is rerolled.
 * All pickups in the room are destroyed. Spawns dice wisps, as well as random types of wisp per pickup destroyed (exact possible types unknown).
 * The wisps turn into golden keys, able to open chests and doors but are destroyed in the process. Wisps are able to open the special door at the start of II or its variants.
 * Spawns sword-like wisps that fire tears.
 * Spawns a black wisp whenever an enemy is killed by effect.
 * Randomly consuming enemies and transforms them into wisps with random effect. Activating creates basic blue wisp.
 * Each wisp spawned has attributes of the active item that was triggered.
 * Spawns stationary a wisp at the location of Isaac from that fires in the direction of Isaac's tears. No limit of wisps persisting. Wisps only last for the current room.
 * The wisps have a card-like appearance, reside within the inner ring, and spawn a card when destroyed.
 * Generates a white wisp that resembles one random boss in this list: Loki, Monstro, Duke of Flies or The Haunt. Loki wisp will fire tears in 4 cardinal directions or diagonal directions, alternating between both; Monstro wisps will fire a cluster of tears like the real Monstro do; Duke of Flies wisps will create blue flies; and The Haunt wisps will fire Brimstone beams that deal 1 damage per tick.
 * All existing wisps are doubled, and a special Diplopia wisp spawns. It is very durable and has double shots.
 * Generates a wisp with a bomb-like appearance and grey aura. Wisps fire small grey tears when Isaac fires tears. When Doctor's Remote is activated, normal tears will fire from the wisps, followed by two separate rounds of larger, lighter grey tears, which explode on contact. Explosions will hurt Isaac. Tears fired from wisps surround the targeted area if close; if Isaac has more than four wisps, the tears will form a circle around the missile.
 * Inner ring. Adds a grey wisp that has extra durability and does not fire. Touching a Curse Room door or spikes will not deal damage, instead destroying the wisp.
 * Spawns a random wisp. Until the end of the run, if destroyed, a new one will spawn whenever a room is cleared.
 * Spawns a pink eraser wisp. Fires tears and erases enemies on contact. Will not be damaged by blocking projectiles.
 * Has a 50/50 chance to either spawn an eternal white-glowing wisp that cannot be destroyed or remove all previously spawned eternal wisps. Wisps spawned from other items cannot be removed.
 * / : Spawns a small white Isaac head wisp after a flip to the form of Tainted Lazarus that is not holding Book of Virtues, even if Flip was not activated manually.
 * Generates brown wisps. Creates 1 wisp, plus 1 additional wisp for each enemy transformed into poop.
 * Spawns a white wisp with Isaac's head. Wisp cannot be destroyed but disappears upon going to the next floor.
 * The wisps are green, and give a +0.1 luck up for each wisp.
 * Spawns large, yellow wisps that will spawn small puddles of yellow creep every two shots. The wisps have little health.
 * Spawns random wisps.
 * Spawns a wisp whenever a charmed enemy dies. Depending on the enemy that dies, the wisp may have a different effect.
 * Inner ring. The wisps are little Pac-Men that fire tears that occasionally inflict fear.
 * Spawns red wisps. When item is used wisps will orbit the Gello familiar instead of Isaac.  If used multiple times in the same room, only the first one spawned will have orbiting wisps.
 * Spawns 3 normal wisps.
 * The wisps are white, firing larger shots that normally does 8 damage. They are very easily destroyed and are all lost at the same time. If Isaac has wisps from other active items, they are not destroyed when Glass Cannon wisps are.
 * Middle ring. The wisps are tiny hourglasses, their shots and destruction petrify enemies.
 * The wisps are yellow and resemble coins. Their tears may inflict a Midas' Touch effect on hit.
 * Outer ring. Spawns fly wisps which shoot normal wisp tears in place of the blue flies it normally spawns. Upon being destroyed wisps spawn a blue fly.
 * Converts one red heart container into three wisps. The wisps have small hearts inside and a large amount of Health.
 * Spawns red wisps that fire red tears. Wisps cause a Head of Krampus effect when destroyed.
 * Spawns hourglass-shaped wisps that cause a room-wide slowing effect when destroyed.
 * Spawns stationary a wisp at the location jumped from that fires in the direction of Isaac's tears. Max of 6 wisps spawned this way. Wisps only last for the current room.
 * Instead of firing tears in a radial pattern, 6 wisps are spawned at the same time. They are destroyed in about 3 seconds, and no more than 6 can be created this way at the same time.
 * The wisps take the appearance of a coin within the outer ring and fire blood tears.
 * Consumes stored hearts to spawn heart wisps, rather than releasing heart pickups. Heart Wisps has a chance to drop a half red heart when destroyed.
 * Wisps will contain the summoned flies, releasing them when destroyed. Each Wisp can contain up to five Blue Flies, for a possible maximum of four Wisps. Enemies killed by wisps will not add any flies to the jar.
 * The wisp amount spawned is doubled with one more added.
 * The wisps appear as sticks of dynamite, firing explosive shots. Although the explosions are small and weak, they can still harm Isaac if too close. The wisps also explode when destroyed.
 * The wisps appear as a coin, glowing in yellow. Wisps fire normal tears.
 * The wisps are purple and leave behind a charm cloud when destroyed.
 * The wisps turn red, firing high-damage tears. Tear damage depends on the charge used when the wisps are spawned; At max charge it does 18 damage per tear.
 * Gives the purple wisps purple homing tears, also buffs the health of the Lemegeton spirits.
 * The wisps are yellow, leave behind a yellow creep and shoot faster.
 * The wisps become coins, but fire normal tears. The wisps have a chance to drop coins when they die.
 * The wisps are pink, but fire tears that have a chance to poison enemies.
 * Spawns 8 golden bomb wisps. When destroyed, the wisp spawns a golden troll bomb which can damage Isaac.
 * Spawns 1 orbiting red wisp upon use, also cleaves each current wisp, doubling them while reducing their damage. After a wisp is split 3 times, repeated uses will extinguish it.
 * Spawns a tiny magenta wisp with high tear height. Upon being destroyed, poisons or freezes enemies in the room.
 * Spawns red wisps that utilize a miniature Brimstone as their weapon, which requires charging and releasing as usual. When Isaac uses Mega Blast, each Mega Blast wisp will continuously fire their Brimstone beam outward as they orbit Isaac.
 * Spawns a wisp based on the item that Metronome chooses. For example, if Metronome chooses, the spawned wisp is a sword that fires sword projectiles. [More info needed]
 * Spawns one glowing green wisp that floats around the room and bounces off walls. Disappears once the room is left. The wisp explodes if hit by Isaac's attacks.
 * The wisps are pills in the inner ring. The wisps come in random colors (Blue, Red, White, Pink, Gray, Light Blue, and Yellow). Each color may fire tears that confuse, poison, petrify, burn, or spawn troll bombs. Like pills, these effects are assigned to a random color each run. May drop a pill when destroyed.
 * The wisps glow red, and fire normal tears with a chance to fire a red, petrifying tear.
 * Spawns three rock wisps that orbit around where the rock was thrown. The wisps stay in place and shoot to the same direction as Isaac, and they despawn after you leave the room.
 * Wisps are black with yellow fire, with chance to fear.
 * Spawns 2 wisps. One wisp looks like the Forgotten's body that has more health. The other looks like the Forgotten's soul that fires normal tear.
 * Spawns a random wisp within the inner ring with a random tear effect. Multiple tear effects can sometimes stack on a single wisp.
 * The wisps are teeth, which shoot teeth at a slower fire rate and deal 12 damage per teeth.
 * The wisps look like small bombs and become mini homing bombs when destroyed.
 * Spawns a wisp that looks like a face in the middle ring and is incapable of shooting tears. The wisp will seek out and open any blocked/locked door, including challenge rooms, item rooms, alt path doors, secret rooms, etc. The wisp can also seek out locked chests and open them. Wisps will extinguish once they have completed their task.
 * Spawns a box wisp in the middle ring. Only spawns a wisp when dropping items from the box.
 * Spawns one rainbow-colored wisp while active. These wisps can take more damage than normal wisps, and deal 15 contact damage per tick. When de-activated, the rainbow coloring slightly fades away.
 * Spawns one random wisp. After used, any destroyed wisps on the same layer have a chance to be replaced with a random wisp after a room is cleared (wisps on other orbits are unaffected).
 * Has a chance to spawn a black (2.5 damage, A Lump of Coal tears), silver (4 damage, Iron Bar tears), gold (3.5 damage, tears turn enemies into gold), red (3.5 damage, laser tears) or cyan (7 damage, quadruple tears) wisp upon breaking a rock. Also spawns a larger wisp with a larger radius when a poop is mined.
 * Spawns one black-colored wisp within the inner ring. If the wisp dies, it activates the Necronomicon effect in the room.
 * Spawns one black wisp that fires nails.
 * Spawns green wisps that temporarily freeze enemies when destroyed.
 * Spawns a wisp in the form of Isaac's floating head that fires piercing spectral tears.
 * Spawns a white wisp that will drop a random pill when extinguished.
 * Spawns 8 red wisps that shoot red tears with 12 damage per tear. Using Plan C will kill Isaac as expected, but wisps won't disappear if used with an item that grants an extra life.
 * Spawns a wisp that uses Baby Plum's diagonal attack whenever the Baby Plum spawned by the flute does the same.
 * The wisps resemble miniature Dips and hover far from Isaac in the outer ring, firing small brown tears that deal 1.5 damage per tear but have a small chance to turn enemies into poop.
 * A different wisp is gained depending on what is won from the slot machine. Because of the varied wisp type, 20 wisps can be generated: an inner ring of 8 and an outer ring of 12. Heart wisps can take an additional hit before extinguishing. Key wisps can take the place of normal keys when colliding with objects. Instead of flies, you get fly wisps, similar to the interaction with guppy's head. [More info needed]
 * Spending a red heart creates an indestructible red wisp that actively follow and damage enemies. It still creates the wisp even if Isaac has no red heart containers, which is likely a bug, as it makes Isaac getting attacking indestructible wisps for free. Especially when they're targeting a monster, the game doesn't recognise them as orbital, so Isaac can create unlimited amount of them.
 * The wisps are white, heart-shaped, hover within the inner ring, fire -esque tears, and are harder to lose.
 * The wisps are red. Wisps fire bloody tears and have higher health.
 * The wisps are red. Wisps fire a small flame similar to the one created by Red Candle. Wisps disappear upon leaving the room.
 * Spawns a red key wisp that fires red tears. The wisp has a chance to unlock a red door while entering an unexplored room.
 * Inner ring. The wisps glow red, appear as bombs, spawn from detonated bombs (cluster bombs and troll bombs do not count), and fire tears that may be detonated mid-flight by re-using the active item.
 * Converts existing wisps to pickups and spawns one red and black wisp.
 * The wisps are black, with a red inverted cross. Each wisp grants you a bonus chance for devil/angel room.
 * The wisps are red, firing small arcing bursts of 2-3 bloody tears.
 * Spawns white-glowing eyeball wisps. Wisps fire normal tears.
 * The wisps appear as a key in white flame, but cannot open locked chests. The wisps fire normal tears. If used without keys, an unlimited amount of wisps can be spawned. This is most likely a bug, as it makes Isaac virtually immune to projectiles by repeatedly spamming the space bar.
 * The wisps are red hearts, sometimes healing Isaac when destroyed. Only creates wisps when Sharp Straw generates a heart.
 * Middle ring. The wisps are yellow and have a chance to drop a random trinket when destroyed.
 * The wisps are white, reside within the outer ring, and act otherwise normally, but fire a smaller Shoop Da Whoop laser along with Isaac when the item is activated again.
 * Spawns a white spider wisp that fires slowing tears.
 * Generates up to eight wisps while charging the item, which are immediately extinguished once the charge runs out. The fire rate of the wisps is based on the speed they're rotating.
 * Spawns one random wisp, then rerolls all Isaac's wisps.
 * Wisps spin as they orbit, firing tears in a fashion similar to the sprinkler itself. The firing rate of sprinkler wisps is faster than normal wisps.
 * A brownish, stationary wisp is left behind when teleporting. The wisp fires in the same direction as Isaac. Wisps spawned this way do not persist through rooms.
 * Spawns red wisps that fire a short laser beam similar to, but significantly smaller.
 * Spawns one red wisp for each lil clot absorbed, up to 8 wisps. One wisp is extinguished every time a lil clot is created.
 * Spawns 3 wisps orbiting where Isaac lands his attack.
 * The pale wisps fire more rapidly, but with a very wide spread.
 * Spawns wisp in middle ring. Wisps have a chance to activate the Tear Detonator effect when being destroyed.
 * Outer ring. Tears caught by Telekinesis become wisps. A maximum of 12 wisps can be collected via this method, but the shield made by telekinesis is smaller than the ring of wisps, wisps frequently block shots from being added as additional wisps.
 * Spawns a purple wisp in the middle ring that fires homing tears.
 * Spawns a flashing blue wisp in the middle ring that fades in and out of existence. Enemies hit by their shots have a chance to teleport to a random location in the room.
 * Same as.
 * Spawns blue-glowing glitched wisps which fire tears with random effects.
 * Same as the wisps, except that they can only be summoned in the middle ring, do not fire tears, and only do 2 contact damage per tick.
 * Middle ring. One wisp spawns for every 2 seconds that the flame is active, up to a maximum of 8 (filling up the middle ring). A wisp will sometimes fire a tiny blue flame instead of a tear. Wisps first spawn upon use of the item, allowing free spawning of wisps by not firing.
 * The souls spawned from Vade Retro fire tears in the same direction as Isaac. No orbiting wisps are spawn upon use.
 * Two wisps orbit the portals, one blue and one orange.
 * Activates the wisp effects of all absorbed items.
 * Spawns a skull wisp that shoots bone tears.
 * Spawns white-glowing wisps that create rock wave when destroyed. These wisps disappear upon leaving the room.
 * Gives a mushroom wisp on the middle ring. Maximum one.
 * Spawns white pony wisps that fire white tears with a chance to fire tears.
 * Wisps are tiny coins with a chance to drop a coin when destroyed. max of 8 at a time
 * The wisps are green-glowing rotten hearts in the middle ring, releasing gas when destroyed. The gas deals no damage.
 * The wisps are red hearts in the middle ring, sometimes healing Isaac when destroyed.

No effect
These combinations simply activate the other item, some of them also spawning a normal wisp.

Synergies

 * Baby-Bender: Wisps gain psychic tears.
 * Increases the tear size and doubles the damage of Wisps.
 * Butter!/'M: Can be used to remove the Book of Virtues as long as Isaac isn't holding a different active item.
 * Doubles the spawned wisps on activation.
 * Forgotten Lullaby: Improves Wisps' rate of fire.
 * The wisps' tears are also detonated; the resulting tears are based on Isaac's own, rather than the wisps'.
 * The wisps' tears are attracted to the magnetic enemy, making it much easier to connect all of the wisps' tears on an enemy.

Interactions

 * : Wisps are unable to shoot diagonally, and will shoot up or downwards instead.
 * NO!: Will not prevent Book of Virtues from spawning, as it's considered a passive item.
 * : Book of Virtues will be removed if it's the oldest collected item, even if another active item is not being held.
 * : The Book of Virtues is considered to be a purely passive item, so only stat boosts will be gained by using Void on it. Further uses of the Void will not have the Book's effects.