Bob's Brain

Bob's Brain is a passive item.

Effects

 * Spawns a familiar that can be fired towards enemies as a projectile.
 * Bob's Brain is fired directly from where Isaac is standing.
 * Bob's Brain is fired directly from where it is located in the chain of familiars behind Isaac, making aiming it slightly more difficult.
 * If it hits an enemy, it deals 3.5 damage and explodes, further damaging and poisoning monsters.
 * The explosion deals 60 damage.
 * The explosion deals 100 damage.
 * The explosion ignores armor.
 * The poison deals double Isaac's damage over time.
 * The explosion can hurt Isaac, dealing a full heart of damage.
 * This can make picking up the item a risky choice, as Bob's Brain will always fire, regardless of whether or not Isaac will be caught in the explosion.
 * Once it explodes, it takes a few seconds to re-appear.
 * Once it explodes, it takes a few seconds to re-appear.

Synergies

 * : The impact damage is increased to 7 and the explosion deals an additional 25 damage.
 * : The explosion deals an additional 85 damage.
 * : Bob's Brain will fire tears upon exploding.
 * Brimstone beams will shoot out upon exploding.

Interactions

 * : No effect.
 * : Explosion damage is halved, with no additional explosions.
 * Duct Tape: Bob's Brain stays in place relative to Isaac until it is fired.
 * /: Bob's Brain will explode upon hitting an enemy that has been turned into poop.

Trivia

 * Three copies of this item are used in BRAINS! (challenge #27).
 * In a Twitter AMA, Edmund McMillen mentioned that Bob's Brain is his favorite item from The Binding of Isaac.