Anima Sola

Anima Sola is an activated item added in The Binding of Isaac: Repentance. starts with this item in the consumable slot.

Effects

 * Chains down the nearest enemy, completely preventing them from acting for 5 seconds.
 * This effect works on enemies that are invulnerable as well, and can alleviate a lot of stress from most trap rooms.
 * While playing as :
 * Anima Sola will always target Dark Esau if he is present.
 * While Dark Esau is chained down, using Anima Sola again will release him and cause him to charge in Tainted Jacob's direction, damaging and burning enemies in its path. This will not use up additional item charges.
 * Dark Esau deals no contact damage to Jacob while chained down.

Synergies

 * : Anima Sola is one of the best items for 9 Volt. Given the long recharge of the item and its duration against an enemy, 9 Volt is extraordinarily effective, reducing the downtime from 10 Seconds to just 2.5 Seconds.

Interactions

 * Anima Sola will visually affect the target with double the chains, but have no additional effect.

Trivia

 * "Anima Sola" translates to "Lone Soul" or "Lonely Soul" in Latin. In a Christian context, it refers to a lone soul stranded and suffering in purgatory.
 * The most popular depiction of this concept also involves both a chain, binding the lone soul's hands, as well as flames, like those following Dark Esau.
 * A splash of color in the chains can also be seen in the Anima Sola's icon, depicting said flames.
 * The Anima Sola shares it name with an enemy from one of Edmund McMillen's other games, The End is Nigh.