Hypercoagulation

Hypercoagulation is a passive item added in The Binding of Isaac: Repentance.

Effects

 * After Isaac takes damage from an enemy or donates health, he drops a red heart that despawns after 1.5 seconds.
 * The heart dropped depends on the source: half-hearts of damage taken drop half-hearts, and full hearts of damage taken drop full hearts.
 * The hearts will get launched out of Isaac with momentum, making them difficult to pick up.

Interactions

 * : Spawns two more full red hearts when Glass Cannon breaks, regardless of how much health was lost to it.
 * /: Rerolled hearts will still disappear.
 * Ace Cards///: Converted/duplicated hearts will not disappear.
 * //: The heart will be converted into a Blue Fly/Spider.
 * : The heart will not be converted to coins.

Synergies

 * /: Damage taken to use the item also spawns hearts, reducing the cost of using them.
 * //Percs! pills: Damage sources that spawn full red hearts will still spawn a full red heart despite the cost being reduced to half a heart.
 * : Can be used to spawn full red hearts for Isaac to pick up. Ideally, this should be done in a confined space so Isaac can easily pick up the heart.
 * : Doubles the healing received from the hearts spawned.
 * /: The hearts will count toward gaining stat boosts/familiars.
 * /Super Magnet: Will immediately start pulling the dropped hearts to Isaac, breaking their momentum and making collection much easier.

Trivia

 * Hypercoagulation (otherwise known as Thrombophilia) is a medical condition that causes blood clots to spontaneously form in a person’s blood vessels and prevents them from dissolving properly.

Seeds
QWDF BT6L (Treasure Room adjacent to spawn)