Buttons

Buttons, originally cut content in The Binding of Isaac: Rebirth, have become a full-fledged feature of The Binding of Isaac: Afterbirth.

Silver Buttons


Silver Buttons appear in trap rooms, which have hazards in them which disarm upon pressing all of the silver buttons in the room. Hazards include: Once pressed, all the hazards will be disarmed - spikes will retract, Red Poop will transform into regular Poop, Red Fire Places will turn into regular Fire Places, Purple Fire Places will turn into Blue Fire Places, and Pitfalls will close.
 * Spikes
 * Retractable Spikes
 * TNT
 * Troll Bombs
 * Megatroll Bombs
 * Stone Grimaces
 * Vomit Grimaces
 * Constant Stone Shooters
 * Gaping Maws
 * Broken Gaping Maws
 * Brimstone Heads
 * Cross Stone Shooters
 * Quake Grimaces
 * Pokies
 * Wall Huggers
 * Slides
 * Grudges
 * Spikeballs
 * Red Poop
 * Red Fire Places
 * Purple Fire Places
 * Pitfalls

Unlike Reward Plates, all Silver Buttons in the room have to be pressed to clear the room even if all enemies are slain.

Red Buttons


Red Buttons usually appear in normal rooms.

Once pressed, all enemies will be killed and all enemy projectiles will be destroyed. Enemies that normally spawn another enemy or shoot projectiles upon death will not do so if slain by a Red Button.

Yellow Buttons


Yellow Buttons only appear in the second or  floor if the player has acquired, and are square-shaped.

Pressing all 3 yellow buttons throughout the floor unlocks the bridge to.

Brown Buttons


Brown Buttons cause certain pits (varies from room to room) to be filled so they can be walked on. Sometimes it clears rocks instead.

Reward Plates (Spawn Buttons)


Reward Plates can appear in a variety of rooms, including Secret Rooms, Curse Rooms, and Shops in Greed mode. When pressed, they may spawn helpful pickups or harmful enemies.

Afterbirth
This list is currently incomplete.


 * 1-3 random Bomb, Heart, Coin, or Key pickups
 * A Donation Machine
 * A Beggar
 * A Slot Machine
 * A Fortune Telling Machine
 * 1-3 monsters or bosses in front of each exit of the room
 * A trapdoor to the next floor
 * Golden poop
 * An item

Afterbirth †
There is a 50-50 chance to spawn a reward or a monster.

Monsters
1-4 monsters or bosses. The Void spawns monsters and bosses based on the room's backdrop.