It's in the Cards

It's in the Cards is challenge #14. Start off with, , , , and 2 random tarot cards. The goal is to defeat Mom. This Challenge is available by default.

Difficulty
A straightforward challenge but no Treasure Rooms, don't be afraid to use cards relatively frequently, as they charge fairly quickly.

Strategy

 * There will be access to cards throughout much of the run. Know what the cards do and use them accordingly.
 * There isn't any special strategy, however it is not a bad idea to reroll until getting the card and until getting great items in a Devil/Angel Room.